Cleveland Browns tight end Jordan Cameron is tackled during a game against the Kansas City Chiefs Oct. 27 at Arrowhead Stadium. The Browns lost, 23-17.Courtesy of MCTThe Drive, The Move, The Decision.Do I need to continue?These moments are painfully seared into the memories of Cleveland fans everywhere and the pain still lingers long after they were made.While I myself have only experienced a few of these heartbreaks as a native Clevelander, the sting of past failures is still felt by people like my father, who experienced The Drive, John Elway and the Denver Bronco’s 98-yard touchdown drive to tie the game in the AFC Championship game in 1987, firsthand.Let’s start with the Cleveland Browns, shall we? A franchise that has never once been to the Super Bowl and has made just one appearance in the playoffs since returning to the shores of Lake Erie in 1999.Being a Browns fan is a lot like believing in Santa Claus as a child. You hope and pray he is real, but deep down you know you will be disappointed when you see a family relative dressed up as Santa giving you a 4-12 record instead of the 11-5 record you asked for multiple times.Disappointment comes with the job description when cheering for the brown and orange. And yes, it is a job trying to cheer for a team that has started 20 different quarterbacks since the 1999 season. Imagine going to a job where your boss is fired every few weeks and a new one is brought in. Imagine this continuing for 15 years, and each year, your product becomes worse to the point where you quit.That is exactly what my father did when the Browns left Cleveland in 1995. He had been a season ticket holder for the Browns for years and when they left, he had just about given up hope. But being the proud Clevelander that he was, he returned for the opening game of the 1999 season when the new Browns made their return to city of rock ‘n’ roll. The brown and orange fell to the hated Steelers that day 43-0 and my dad has not attended a Browns game since. Can you blame him?But while the Browns have struggled for years, it wasn’t until The Decision, LeBron James “taking his talents” to Miami, that the Cleveland Cavaliers fell from the ranks of the NBA playoff regulars.The Cavaliers selected Anthony Bennett with the first overall pick in 2013, a player who averages only 4.1 points per game in 12.7 minutes played. In the words of Forrest Gump, “And that’s all I have to say about that.”The one team that seems to be Cleveland’s only hope of being a successful sports town anytime soon is the beloved Cleveland Indians. The franchise that has not won a World Series since 1948 came within three outs of bringing the trophy back to Cleveland in the 1997 World Series before Jose Mesa and Charles Nagy quite literally threw the game away, allowing the Florida Marlins to celebrate a championship in just their fifth year of existence.But there is room for optimism at Jacobs Field in 2014 (I know, I know its “Progressive Field” now, but if you are any kind of Tribe fan it is still “The Jake” to you) coming off of an appearance in the playoffs in 2013. Although their berth in the American League Wild Card Game ended in defeat as the Tribe fell to the Tampa Bay Rays last season, the likes of former Buckeye Nick Swisher and 2013 All-Star Jason Kipnis have given Tribe fans a reason to cheer again and get excited about a team that has been so close to a title for so long.So to all you non-Cleveland fans out there who are disappointed when your team loses in the postseason or doesn’t bring home a title, don’t despair. Be happy you don’t cheer in a city that hasn’t won a major championship since 1964 — when the Browns won an NFL championship in the pre-Super Bowl era. And to all of my fellow Clevelanders out there who are desperate for a winner, remember our mantra as the Indians take the field this week:“There’s always next year.”
Is there any one place that offers the sight of the rich and diverse flora and fauna of India, all at once? Well, all the wild, endangered and beautiful species are on board a special train to meet the young and curious in Delhi. To revive an innovative exhibition on rail that started last year, Science Express Biodiversity (SEBS) is being relaunched in its second phase on Tuesday, 9 April.It is a 16 coach train with eight coaches dedicated to interactive exhibits carrying shorts films, videos, kiosks and back lit panels to showcase the biodiversity of India. The highlight is the Joy Science Lab which is an open platform for students to perform guided experiments and revel in the myriad of activities thrown open to them. Also Read – ‘Playing Jojo was emotionally exhausting’A group of dignitaries are expected to grace the flag off ceremony from Safdarjung on 9 April; the expected list includes Minister of Environment and Forests, Jayanthi Natrajan and Chief Minister of Delhi, Sheila Dikshit.This train will be stationed at the Pragati Maidan railway station from 10 to 13 April for a free of cost exhibition of the biodiversity of India. It has on board a team of 40 young and qualified science intellectuals to facilitate the visitors throughout the journey.
Kolkata: A six-year-old girl student was allegedly molested by a male teacher at a school in south Kolkata which triggered protests by angry parents in front of the institution, police said. Ananya Chakrabarty, Chairperson of the West Bengal Child Rights Commission, said that the student had been molested by the male teacher. The accused teacher was taken to a police station and investigation was on, police said. The police had a tough time to control the protestors who tried to enter the school. Brickbats were hurled at the police personnel in which some of them were injured, the sources said. The police had to wield batons to disperse the demonstrators. Deputy Commissioner of Police(South East division) Kalyan Mukherjee said, “The teacher was taken to the police station. Investigation is on”. The school authorities were not available for immediate comments.
August 13, 2014 Free Webinar | Sept. 9: The Entrepreneur’s Playbook for Going Global 2 min read Growing a business sometimes requires thinking outside the box. Ever feel as though your business attire is slightly too stinky or wrinkly to re-wear — even if a trip to the dry cleaner isn’t quite yet necessary? Procter & Gamble is bringing to market a brand new device, the curiously-named Swash, to suit this very need.Priced at $500, P&G likens the machine to a “microwave” for clothes, reports The Wall Street Journal, in the sense that it seeks not to “replace laundering or dry cleaning…just delay them.”The machine sprays fluids from gel-filled Tide pods — priced at $6.99 for a pack of 12 — onto garments to remove wrinkles and odors and restore fit. The Swash then dries each item — at four feet tall, it is large enough to fit one extra-large men’s suit jacket — in 15 minutes or less using thermal heating technology.“Say goodbye to excessive washing, drying, steaming, ironing and dry-cleaning,” the company writes on its website, “and say hello to living life unhampered.”Related: 3 Unusual Ways Smart Tech Meets FashionWith Swash, P&G says it is targeting a brand new demographic, which it has termed “re-wearers.”“Two decades ago,” P&G’s research director, Mike Grieff, told the Journal, “the idea of wearing clothes several times before washing them had a negative stigma.” Now, especially among business people with capsule wardrobes of high-quality items, the pragmatics of re-wearing have become more socially acceptable.It remains to be seen, however, whether the Swash will forge a brand new phase in users’ clothes-caring routines — especially at such a steep cost and considering its rather limited claims.Created in collaboration with Whirlpool, the Swash is currently available at Bloomingdale’s and will roll out to other retailers next month, P&G said.Related: Banana Republic Thinks Your Typical ‘Startup Guy’ Should Dress Like This Register Now »
14Sep House approves Rep. Lucido bill to end parental rights in FGM cases Categories: Lucido News,News The state House today overwhelmingly supported legislation by state Rep. Peter Lucido which allows the termination of parental rights for anyone who has their child undergo a female genital mutilation (FGM).“A female genital mutilation has no places in the United States, Michigan and especially in a family’s home,” said Lucido, vice chair of the House Law and Justice Committee. “Nobody who forces their child to undergo this procedure should be legally allowed to be a parent to that child. This legislation allows for the revocation of parental rights in the best interest of the child.”The bill follows a seven-bill bipartisan legislative package signed into law in June which criminalized the act of a female genital mutilation – any procedure performed on girls intended to remove or damage the external female genitalia. Lucido voted in support of the package, but believes a conviction should have an added penalty for a parent or guardian.“The legislation we approved addressed the act of the FGM itself, transportation to the act, removal of medical license, and extending the statute of limitations for civil and criminal justice for the victims,” Lucido said. “What about the parents who do this? They don’t deserve to be a parent and we had to impose that as an option in state law.”The previously approved FGM legislation, and Lucido’s bill, follow a February incident where two young girls from Minnesota were subjected to the procedure at a southeast Michigan clinic. A Livonia couple was arrested on federal charges in April after performing the procedure afterhours at their medical clinic, while a third individual has been fired from their emergency room doctor position for performing the procedure at the same Livonia clinic.House Bill 4716 advances to the state Senate for its review.###
Source:https://www.en.uni-muenchen.de/ Reviewed by James Ives, M.Psych. (Editor)Oct 25 2018Spending long periods in space not only leads to muscle atrophy and reductions in bone density, it also has lasting effects on the brain. However, little is known about how different tissues of the brain react to exposure to microgravity, and it remains unclear whether and to what extent the neuroanatomical changes so far observed persist following return to normal gravity. In cooperation with Russian colleagues and with neuroscientists based at the University of Antwerp led by Floris L. Wuyts, LMU neurologist Professor Peter zu Eulenburg has completed the first long-term study in Russian cosmonauts. In this study, which appears in the New England Journal of Medicine, they show that differential changes in the three main tissue volumes of the brain remain detectable for at least half a year after the end of their last mission.The study was carried out on ten cosmonauts, each of whom had spent an average of 189 days on board the International Space Station (ISS). The authors used magnetic resonance tomography (MRT) to image the brains of the subjects both before and shortly after the conclusion of their long-term missions. In addition, seven members of the cohort were re-examined seven months after their return from space. “This is actually the first study in which it has been possible to objectively quantify changes in brain structures following a space mission also including an extended follow-up period,” zu Eulenburg points out.The MRT scans performed in the days after the return to Earth revealed that the volume of the grey matter (the part of the cerebral cortex that mainly consists of the cell bodies of the neurons) was reduced compared to the baseline measurement before launch. In the follow-up scans done 7 months later, this effect was partly reversed, but nevertheless still detectable. In contrast, the volume of the cerebrospinal fluid, which fills the inner and outer cavities of the brain, increased within the cortex during long-term exposure to microgravity. Moreover, this process was also observable in the outside spaces that cover the brain after the return to Earth, while the cerebrospinal fluid spaces within returned to near normal size. The white matter tissue volume (those parts of the brain that are primarily made up of nerve fibers) appeared to be unchanged upon investigation immediately after landing. However, the subsequent examination 6 months later showed a widespread reduction in volume relative to both earlier measurements. In this case, the researchers postulate that over the course of a longer stint in space, the volume of the white matter may slowly be replaced by an influx of cerebrospinal fluid. Upon return to Earth, this process is then gradually reversed, which then results in a relative reduction of white matter volume.Related StoriesAn active brain and body associated with reduced risk of dementiaResearchers measure EEG-based brain responses for non-speech and speech sounds in childrenRush University Medical Center offers new FDA-approved treatment for brain aneurysms”Taken together, our results point to prolonged changes in the pattern of cerebrospinal fluid circulation over a period of at least seven months following the return to Earth,” says zu Eulenburg. “However, whether or not the extensive alterations shown in the grey and the white matter lead to any changes in cognition remains unclear at present,” he adds. So far the only clinical indication for detrimental effects is a reduction in visual acuity that was demonstrated in several long-term space travelers. These changes may very well be attributable to the increased pressure exerted by the cerebrospinal fluid on the retina and the optic nerve. The governing cause for the widespread structural changes in the brain following long spaceflights might lie in minimal pressure changes within the body’s various water columns under conditions of microgravity that have a cumulative effect over time. According to the authors, to minimize the risks associated with long-term missions and to characterize any clinical significance of their structural findings, further studies using a wider range of diagnostic methods are deemed essential.
By Dr. Ananya Mandal, MDDec 11 2018A large new study has shown that sex work criminalization is associated with increased incidences of violence against them. Since most of the sex workers are unable to screen their potential clients and resort to obscure and hidden places, they are more vulnerable to crimes against them, finds the study.These sex workers are also at a greater risk of poor health and abuse in nations where sex work in not legalized. The study titled, “Associations between sex work laws and sex workers’ health: A systematic review and meta-analysis of quantitative and qualitative studies,” was published in the latest issue of the journal PLOS Medicine.Related StoriesIt is okay for women with lupus to get pregnant with proper care, says new studyScripps CHAVD wins $129 million NIH grant to advance new HIV vaccine approachPatients with HIV DNA in cerebrospinal fluid have high risk of experiencing cognitive deficitsThe researchers from the London School of Hygiene and Tropical Medicine have noted that sex workers also suffer from other social factors such as arrest, imprisonment and extortion by law officers and are a vulnerable group because of the lack of legalization of their trade. The study notes that these women are three times more likely to be victims of sexual and physical violence from a client and are also at risk of getting HIV or other sexually transmitted infections compared to sex workers living in nations where it is legalized and tolerated.The researchers also found that in nations such as Canada where it is criminalized but a Nordic model is followed, these workers are also at risk. Under this model, which was started by Sweden, the client can be arrested for a criminal offence but the sex worker cannot be arrested. Canada also made it illegal to pay for sex in 2014 making things riskier for the sex workers. This puts them at risk of risky encounters and extortion, the authors of the study explain. This Nordic model is followed by France, Iceland, Northern Ireland, Norway and the Republic of Ireland as well. Regulated sex work is allowed in Guatemala, Mexico, Turkey and the US state of Nevada. Sex work is decriminalized only in New Zealand but the law is not applicable for migrants.Lucy Platt, associate professor in public health epidemiology, and Pippa Grenfell, assistant professor of public health sociology were the authors of this study. They looked at data from 33 different nations and also interpreted the comments and statements from the sex workers who participated in these studies. There were 9 studies and a total of over 5,000 participants in the study which showed violence against sex workers. Risk of HIV and sexually transmitted infections due to condom-less sex was seen in 9,447 participants from 4 different studies.The researchers concluded, “There is an urgent need to reform sex-work-related laws and institutional practices so as to reduce harms and barriers to the realisation of health.” They add, “The removal of criminal and administrative sanctions for sex work is needed to improve sex workers’ health and access to services and justice.” Source:https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1002680
Reviewed by Kate Anderton, B.Sc. (Editor)Jan 11 2019Research led by Suresh Alahari, PhD, the Fred Brazda Professor of Biochemistry and Molecular Biology at LSU Health New Orleans School of Medicine, has found a new role for a protein discovered by his lab in preventing the growth and spread of breast cancer. The results of the study, which could have a significant impact on cancer therapy, are published in the OnlineFirst section of the journal Cancer Research, available at http://cancerres.aacrjournals.org/content/early/2019/01/11/0008-5472.CAN-18-0842.Dr. Alahari discovered the novel protein, Nischarin, which is involved in a number of biological processes including the regulation of breast cancer cell migration and movement. Although his lab has shown that Nischarin functions as a tumor suppressor, research continues to uncover new information that may lead to better treatments.Related StoriesLiving with advanced breast cancerStudy reveals link between inflammatory diet and colorectal cancer riskUsing machine learning algorithm to accurately diagnose breast cancerIn the current study, the research team investigated Nischarin’s function in exosome release. Exosomes are nano-sized vesicles (fluid-filled sacs) containing proteins, genetic and other material involved in both physiological and pathological processes. Tumor-derived exosomes contain various signaling messengers for intercellular communication involved in tumor progression and metastasis of cancer. Tumor exosomes influence the interactions of various types of cells within the tumor microenvironment, regulating tumor development, progression and metastasis. Primary tumors release exosomes that can enhance seeding and growth metastatic cancer cells.Among the researchers’ findings: Nischarin regulates cell attachment and alters the properties of exosomes. Exosomes from Nischarin-positive cells reduce breast cancer cell motility and adhesion, as well as tumor volume. Nischarin-positive cells release fewer exosomes, and cell survival is decreased. Co-culturing breast cancer cells with Nischarin-positive exosomes decreases tumor growth and lung metastasis.”This novel role for the tumor suppressor Nischarin not only increases our understanding of the exosome biology, but can be translated to identifying new targets for modulating cancer metastasis,” notes Dr. Alahari. “Inhibition of the secretion of exosomes may serve as an effective treatment for cancer.”According to the National Cancer Institute’s Surveillance, Epidemiology, and End Results (SEER) Program, which includes data from LSU Health New Orleans’ Louisiana Tumor Registry, breast cancer represented 15.3% of all new cancer cases and 6.7% of all cancer deaths in 2018. There were an estimated 266,120 new cases of breast cancer in the US and an estimated 40,920 deaths.”It has been shown that exosomes can be developed as carriers for delivering drugs,” Alahari adds. “Nischarin-expressing exosomes in combination with drugs will likely have very good therapeutic effect on breast cancer patients.” Source:https://www.lsuhsc.edu/newsroom/Research%20to%20Advance%20Cancer%20Therapy.html
March 31, 2019 COMMENT Defence Ministry, Presidential Palace and Home Ministry buildings pictured after the lights were turned off during Earth Hour in New Delhi. – Reuters The power distribution companies in the national capital saved 258 megawatt (MW) of electricity during sixty minutes of the Earth Hour observed on Saturday night. Government and private institutions as well as people kept their electric appliances switched off during the Earth Hour observed from 8.30 pm to 9.30 pm.The two BSES discoms managed to save 161 MW power during the hour, said a BSES spokesperson. The BSES Rajdhani Power Limited saved 92 MW while the BSES Yamuna Power Limited saved 69 MW electricity during the Earth Hour, he said. The two discoms supply power to major portion of the city.The Tata Power Delhi Distribution Limited (TPDDL) supplying to North and north-west Delhi areas saved 98 MW electricity during Earth Hour, a company spokesperson said. “Lakhs of consumers and Several RWAs in our area joined us in the campaign and switched off lights during the Hour which resulted in a saving of 98 MW. I thank them for their participation in this global combat climate change Initiative,” said Sanjay Banga, CEO of TPDDL. Last year, the TPDDL had saved 70 MW power during the Earth Hour. Published on COMMENTS SHARE SHARE EMAIL power and distribution SHARE